Sr. Manager, Clinical Bioinformatics

Lead the design, implementation, and optimization of bioinformatics pipelines for single-cell and spatial genomics data, from raw data to clinical interpretation. Establish, maintain, and operate CLIA-compliant computational workflows, documentation, and quality systems in collaboration with the CLIA Laboratory Director Be responsible for data quality control and patient data reporting Develop and validate algorithms, statistical models, and quality metrics for clinical assay performance. Direct analytical validation of bioinformatics components in support of LDT assays. Ensure computational reproducibility, version control, and auditability aligned with CLIA and CAP standards. Build and lead a high-performing team of bioinformaticians, fostering technical excellence and accountability. Partner with broader R&D computational biology team for method development and platform improvements Define team goals, deliverables, and metrics supporting diagnostic R&D milestones. Establish data management and computational infrastructure in collaboration with IT, Quality, and CLIA lab teams. Support publication-quality analyses and contribute to scientific manuscripts and presentations at major conferences. Detail-oriented and quality-driven, with a deep respect for validation and rigor. Strategic thinker who also thrives in hands-on analytical and computational work. Effective communicator and collaborator across scientific, operational, and executive teams. Motivated by building new capabilities at the intersection of genomics, computation, and clinical medicine. Work closely with clinical, laboratory, and assay development teams to design studies, interpret results, and implement findings into diagnostic workflows. Collaborate with regulatory and quality leaders to ensure data integrity and compliance in all analytical systems. Contribute to defining the broader clinical bioinformatics strategy and diagnostic roadmap for 10xDx. Manager of Clinical Bioinformatics will ensure that data analysis pipelines, algorithms, and interpretation frameworks meet the highest scientific and quality standards--enabling 10x to deliver clinically meaningful insights that advance precision medicine.