2026 Summer Intern Translational Research, In-Vitro Disease Modeling (PhD student)

About Us 

Position Title: 2026 Summer Intern – Translational Research, In-Vitro Disease Modeling (PhD student)

Department: Translational Sciences

Reports To: Scientist, Biology

Location: South San Francisco, CA – On-site 5 days per week

Job Overview

Kardigan is seeking a Research Intern to contribute to our translational cardiovascular research platform through a focused project comparing valve interstitial cell (VIC) behavior using advanced in vitro culture systems. Valvular heart disease represents a significant unmet medical need, and this internship offers a unique opportunity to generate foundational knowledge that will advance the field's understanding of valve cell biology. You'll work hands-on with primary cells, advanced biomaterials, and state-of-the-art imaging techniques while collaborating with a team of scientists dedicated to developing targeted treatments for cardiovascular diseases.

What You’ll Do

• Isolate, culture, and maintain primary valve interstitial cells


• Fabricate advanced biomaterial constructs and encapsulate and maintain primary cell cultures


• Perform immunofluorescence staining to assess phenotype, execute high-content confocal imaging and quantitative analysis


• Conduct molecular biology assays including Western blotting and qPCR for quantitative gene and protein expression analysis


• Maintain accurate and detailed experimental records in electronic lab notebooks with adherence to best practices in data documentation


• Prepare summary figures, analyze data, and present findings to the broader research team at end-of-summer presentation

Qualifications

• Currently pursuing a Ph.D. in Biomedical Engineering, Biology, Biochemistry, Biomaterials, or related field


• Essential: Proven experience with hydrogels, biomaterials, or 3D culture systems


• Demonstrated hands-on experience with sterile technique and mammalian cell culture (primary cell experience preferred)


• Hands-on experience with immunofluorescence, microscopy, and molecular biology techniques (Western blot, qPCR)


• Strong organizational skills, attention to detail, and ability to maintain accurate experimental records


• Ability to work independently and collaboratively in a fast-paced research environment


• Excellent communication skills and enthusiasm for learning new techniques


• Available for 10-12 weeks during summer 2026

Pay: $38 per hour
Location requirement: Candidates must be based in the San Francisco Bay Area (no relocation assistance)