Co-op, Technical Development ASO

Position Summary:

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Assist in with small scale synthesis of oligonucleotides (ASO and siRNA).  Responsibilities include operating synthesizer, preparing reagents, running HPLC/LC-MS and maintaining documentation.  The co-op will gain exposure to synthesis and analysis of ASO using automated synthesizer and a variety of analytical and purification instruments. 

Work Model: 

Core Lab & Ops: This role typically requires that the majority of the work be conducted on-site.

Responsibilities:

• Synthesize, purify, and characterize oligonucleotide constructs. 


• Record experimental data, procedures and results in Electronic Notebook (ELN). 


• Performed desalting operations using TFF (tangential flow filtration). 


• Prepare reagents/buffers for synthesis and characterization methods. 


• Summarize data in presentations and technical reports. 

Requirements:

• Graduate or Undergraduate student in, Biochemistry, Chemical Biology program with an emphasis on Organic Chemistry and interest in oligonucleotide synthesis, with at least two years of coursework completed.
  
  
  
  • This is a 6 month co-op, starting July 6, 2026 working full-time (40 hours per week) until December 18, 2026
  
  
  
  


• Understanding of organic chemistry, biochemistry, analytical chemistry and oligonucleotide synthesis. 


• Previous lab experience. At least 3 months of laboratory experience, 6 months prefer. 


• Strong attention to detail, organization and adherence to safety protocols. 


• Prior experience with characterization of organic molecules with H/UPLC and LC-MS is a plus. 


• Knowledge of basic laboratory equipment, pH meter, balances, pipets,


• ASO and siRNA experience a plus

U.S. Hourly Wage Range: 

• $23.00-$30.00/hour. The estimated hourly range reflects an anticipated range for this position. The actual hourly wage offered will depend on the candidate’s school year/level.

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