Intern, Computational Biology

Company Overview:

Strand Therapeutics is a clinical stage biotechnology company utilizing synthetic biology to genetically program mRNA to deliver truly revolutionary immunotherapies to patients.

Building on the idea of creating smart therapies based on Boolean logic circuits, Strand was started by biological engineers working together at MIT who were seeking to apply the concept of the emerging field of mRNA therapeutics. Strand's technology is therapeutic-area and mRNA modality agnostic where therapeutic proteins are encoded onto modified, self-replicating, or circular mRNA backbones which in turn are programmed with cell-specific sensors and circuits.

Today, Strand has established multiple programmable mRNA platforms with one clinical stage asset and several programs in preclinical development as well as early discovery. Our lead program, STX-001, is currently being evaluated in a Phase 1 clinical trial for solid tumors. Our corporate headquarters is located in the Fenway district of Boston, Massachusetts.

Become the next standout single strand!

Job Summary:

Strand is looking for people who have the enthusiasm and motivation to be a highly contributing member of a team with significant impact on Strand’s cell engineering programs. This opportunity will offer the employee the ability to work in a cross-functional environment and be a part of the future strategy of the company.

We are looking for an Intern, Computational Biology to join the Computational Biology team at Strand Therapeutics. The incoming candidate will incorporate data, including from next-generation sequencing (NGS), flow cytometry, imaging, and bioanalytical assays, into existing mathematical models of therapeutically relevant genetic circuits. The candidate will be expected to work in an innovative, fast-paced, cross-collaborative biotech environment.

Primary Responsibilities:

• Incorporate NGS data as well as data from other sources into existing mechanistic and statistical/ML models of therapeutically relevant genetic circuits.


• Refine mathematical models to better predict genetic circuit behavior in different contexts.


• Engage with cross-functional project teams to support data-driven modeling of biological systems.

Qualifications:

• On track to graduate with a Ph.D. or M.S. in Computational Biology, Biological Engineering, Synthetic Biology, Chemical Engineering, Statistics, or a related discipline; or a B.S. with multiple years of relevant industry experience. Experience in the biotechnology space is a plus.


• Familiarity with modeling biological systems; familiarity with mammalian regulatory biology and genetic circuit design is a plus.


• Proficiency in programming languages (Python) as well as modern software development techniques and Unix systems (Git, Linux, shell scripting, etc.). Familiarity with high-performance computing (HPC) and cloud computing (AWS) is a plus.


• Strong collaboration and inter-personal skills. Ability to present data science and computational concepts to a diverse audience.


• Ability to multi-task and prioritize to meet important deadlines

Strand Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Strand does not accept unsolicited resumes from any source other than directly from candidates.

Job Type: Intern

Hourly Rate: $30 - $33 per hour