We are seeking an experienced oligonucleotide chemist or pharmaceutical chemist with expertise in design, synthesis, analysis of oligonucleotides. The candidate should have expertise in scientific literature, database and patent search; modern analytical and separation techniques and instrumentation. Successful candidate will work in a multidisciplinary environment involving discovery and development of RNAi chemical modifications, delivery agents and conjugates.\n\nSummary of Key Responsibilities:\n\n * Synthesis of oligonucleotides and conjugates; knowledge in formulation, analysis of drug delivery systems and conjugates for nucleic acids. \n\n * Purification of oligonucleotides using modern separation techniques\n\n * Analysis and characterization using modern analytical techniques (NMR, MS, HPLC, IR, etc.). \n\n * Multitasking and multidisciplinary expertise\n\n * Expertise in scientific data base, literature survey and patent search\n\n * Manuscript Writing skills\n\n\n\n\nLearning Outcomes\n\n 1. siRNA synthesis\n 2. siRNA analytical chemistry and characterization\n 3. siRNA formulations\n\n\n\nQualifications\n\n * Advanced degree in oligonucleotide chemistry or pharmaceutical chemistry. Graduate or PhD candidates preferred.\n\n * Hands-on experience on separation and analytical instrumentation and scientific database search\n\n * Instrumentation skills, desire to learn bioassays, oligonucleotide synthesis\n\n * Legal authorization to work in the U.S.\n\n * At least 18 years of age prior to scheduled start date\n\n\n\n\nU.S. Pay Range\n\n$30-$35/hr\n
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