LNP Intern

We are seeking a motivated intern to apply their classroom knowledge in drug delivery, biomaterials, and formulation to contribute to developing delivery systems for LETI’s in vivo gene editing therapeutics in our state-of-the-art LNP delivery laboratory. This is a unique opportunity to gain hands-on experience and learn from seasoned drug delivery experts, with a focus on non-viral delivery technology development. 

Here’s What You’ll Do:  

• The successful candidate will learn the workflow of our LNP delivery lab and shadow experienced scientists 


• Execute established protocols, under supervision, and work on LNP production and downstream processing 


• Characterize RNAs encapsulated LNPs for their size, zeta potential, encapsulation efficiency, integrity, and stability using conventional assays, e.g., dynamic light scattering (DLS), ribogreen assay, etc. 


• Perform primary T-cell culture, transfection studies, and downstream flow cytometry analysis 


• Adherence to good documentation practice 


• Maintain data integrity and rigor  


• Data entry into Benchling (electronic notebook) 


• Generation of summary data with subsequent report 


• Presentation at research meetings 


• Attend Technology Development, cross-functional, and company meetings 

Requirements: 

• Working towards a BSc, or BME degree in pharmaceutics, chemistry, bioengineering, or equivalent 


• Hands-on experience with LNPs is preferred, but not required 


• Organized, independent, and collaborative 


• Excellent written and verbal communication skills 


• Curiosity and diligence