Research Fellow (Lipid/Polymer Synthesis)

The Laboratory for RNA Delivery Therapeutics @ NTU

Prof Mary Chan-Park and her team have recently won a highly competitive large grant on the design, synthesis and studies of the improved RNA delivery vehicles. We are looking for post-doctoral fellows to design and synthesize new lipids or polymers that are stimuli-responsive and suitable for nanoparticle delivery formulations. New alternative delivery vehicles for the promising RNA nanomedicine are urgently needed to replace the current ones to achieve great delivery efficacy with less side effects. We have shown that some polymeric or lipid nanoparticles are excellent candidates as delivery agents.

This research will be in collaboration with other top international scientists from MIT, and Boston University.

Dr Mary Chan-Park is currently the Centre Director of the Centre for RNA Delivery Therapeutics. She is also the current President Chair Professor of Chemistry, Chemical Engineering and Biotechnology (2024 onwards) and the 2019 Board of Trustees Chaired Professor of Chemical and Biomedical Engineering (2019-2024), both at the Nanyang Technological University Singapore (NTU Singapore). She also holds a joint appointment at the Lee Kong Chian School of Medicine at NTU.  She is the Director of the Centre for Antimicrobial Bioengineering and the Director of the NTU Laboratory for RNA Delivery Therapeutics. She is a Fellow of the America Institute of Medical and Biological Engineering.

Key Job Purpose - We are looking for Research Fellows for the lab to conduct research in the design and synthesis of novel lipids or polymers for novel stimuli-responsive delivery vehicles for RNA therapeutics.

Key Responsibilities:

• Design and synthesis of new Lipid or polymer

• New design stimuli-responsive lipids or polymers for nanoparticle delivery formulations

• Develop optimum formulations for RNA delivery

• Nanoparticle characterisation

Job Requirements:

• PhD (for Research Fellow and above equivalent) qualification degree in Chemistry, Chemical Engineering, Materials Science or related field

• At least 5 years of relevant experiences in PHD or beyond / technical hands-on experience in Synthesis and Design of new lipids and polymers for stimuli-responsive nanoparticle Delivery Formulations

• Familiarity with synthesis and design of advanced lipids or polymers that are stimuli-responsive, or for RNA delivery formulations and evaluation (e.g. top research groups and classical LNP formulations)

• Good written and oral communication skills (if applicable)

• Proficiency in Lipids or Polymers synthesis is a pre-requisite

• Competent in oral / written technical communications, and technical leadership (required to supervise junior researchers, like PHD students).

• Interpersonal skill (e.g. Ability to work independently / develop solutions under strict timelines, meticulous and eye for details / excellent organizational / time management skills)

• Entry level PHD graduating candidates are welcome to apply

For Senior Research Fellow,

• Ability to supervise PHD students

• Ability to build rapport and influence stakeholders at all levels

• Ability to work collaboratively in a fast-paced environment.

• Possesses international experience, with a strong network of contacts in the region.

• Possesses international experience, with a strong network of contacts in the region.

We regret to inform that only shortlisted candidates will be notified.