(Senior) Scientist, Computing & Intelligence, IHPC

Job Summary

About the Role

The Institute of High Performance Computing (IHPC), A*STAR, is seeking a highly motivated Senior Research Scientist to conduct cutting-edge research in Artificial Intelligence and Machine Learning, with a focus on advancing AI-driven scientific discovery across healthcare, life sciences, biology, and biomedical research.

The successful candidate will lead the development of next-generation AI technologies, including foundation models, multimodal learning systems, scientific machine learning, generative AI, and agentic AI systems that accelerate scientific discovery and translate research innovations into real-world impact.

Key Responsibilities

Research & Innovation

• Develop AI models and platforms that accelerate discovery in healthcare, life sciences, and biomedical research.
• Advance foundation models that learn from large-scale biological, clinical, molecular, and scientific datasets.
• Develop AI systems for:
• Multi-omics analysis
• Drug discovery and therapeutic development
• Precision medicine
• Biomarker discovery
• Disease prediction and prognosis
• Scientific knowledge extraction and reasoning
• Build agentic AI systems capable of hypothesis generation, experiment design, scientific reasoning, and autonomous discovery.
• Develop methodologies that integrate experimental data, simulations, scientific literature, and domain knowledge to support scientific decision-making and discovery.

• Collaborate with clinicians, biologists, healthcare researchers, and domain scientists to translate AI innovations into real-world applications.
• Drive the development of reusable AI platforms, foundation models, and scientific discovery systems.
• Contribute to technology transfer, intellectual property generation, and commercialization opportunities.
• Lead collaborations with academic institutions, healthcare organizations, government agencies, and industry partners.

Scientific Leadership

• Publish high-impact research in leading AI, machine learning, healthcare, and scientific journals and conferences.
• Contribute to grant proposals, project planning, and strategic research initiatives.
• Mentor junior researchers, engineers, and students.
• Represent IHPC in collaborations with academic, healthcare, government, and industry partners.

Requirements

Essential

• PhD in Computer Science, Artificial Intelligence, Machine Learning, Data Science, Computational Biology, Biomedical Engineering, Computer Engineering, or a related discipline.
• Strong track record in AI/ML research demonstrated through publications, patents, or impactful projects.
• Strong programming skills in Python and modern machine learning frameworks such as PyTorch or TensorFlow.
• Experience developing and evaluating machine learning and deep learning models.
• Experience working with large-scale datasets and computational infrastructure.
• Strong interest in applying AI to scientific discovery, healthcare, and life science challenges.

Preferred

• Experience in one or more of the following areas:Foundation Models for ScienceComputational Biology and Multi-OmicsDrug Discovery and Molecular ModelingBiomedical AIPrecision MedicineScientific Knowledge GraphsScientific Reasoning and Agentic AI SystemsHealthcare AI and Clinical Decision SupportGenerative AI for Scientific Discovery

What We Offer

• Opportunity to work on nationally significant AI for Science, Healthcare, and Life Sciences initiatives.
• Access to world-class computational infrastructure, large-scale scientific datasets, and advanced research facilities.
• Collaboration with leading AI researchers, clinicians, scientists, and industry partners.
• A dynamic environment supporting both fundamental AI research and translational impact.
• Opportunities to shape the future of AI-driven scientific discovery and healthcare innovation.